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SCIB Terminates Indonesian Project

indie
2 minutes

KUCHING, MALAYSIA, Feb 14, 2023 - (ACN Newswire via SEAPRWire.com) - Civil engineering specialist Sarawak Consolidated Industries Berhad (SCIB) today announced that the Company's wholly-owned subsidiary, SCIB International (Labuan) Ltd. (SCIBILL), has issued a notice of termination to PT Cipta Multi Sarana (PTCMS) for the proposed engineering, procurement, construction and commissioning (EPCC) project involving earthworks for the Prabumulih-Muara Enim tolled road located in Sumatera, Indonesia valued at RM55.59 million.Group MD and CEO of SCIB, Encik Rosland bin OthmanSCIBILL, which accepted a letter of award for the EPCC project on 18 August 2020 from PTCMS, has decided to take the necessary measures to protect its interests following the lack of progress in the project arising from uncertainties related to the COVID-19 pandemic and in view of the initiatives being taken to review and update SCIB's order book records.SCIBILL and PTCMS have mutually agreed to terminate the contract and unconditionally release and indefinitely discharge both parties from all claims, liens and obligations of every nature arising out of or in connection with the performance of the works and all amendm...

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ONERHT Foundation together with Chui Huay Lim Club and Ee Hoe Hean Club raise close to S$500,000 to promote medical care and support for disadvantaged groups

indie
4 minutes

SINGAPORE, Feb 14, 2023 - (ACN Newswire via SEAPRWire.com) - ONERHT Foundation Ltd, the corporate social responsibility vehicle of RHTLaw Asia LLP and the RHT Group of Companies (collectively, "ONERHT"), together with its co-organisers Chui Huay Lim Club and Ee Hoe Hean Club, has raised close to S$500,000 to promote health and wellness among disadvantaged and vulnerable members of our community.Guest-of-Honour Mr Ong Ye Kung, Minister for Health, (7th from left) onstage with Organising Committee members and advisors, generous donors and the esteemed artists at the eventThe charity gala dinner held on 8th February 2023 was themed "In Pursuit of Excellence - ONERHT Foundation Charity Gala Dinner 2023" and attended by Guest-of-Honour Mr Ong Ye Kung, Minister for Health together with more than 400 guests.Funds raised through the event will be used to support three local charitable healthcare institutions: Singapore Thong Chai Medical Institution, Ren Ci Hospital and Kwong Wai Shiu Hospital. Each with its own storied history of service to the community, these three institutions serve thousands of patients every month, regardless of background, race and religion. The funds will enable th...

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Davey Perkins’ NFT Auction Ended in Just One Minute on playNomm NFT Marketplace For a High Buy Out Price

pandora
3 minutes

NFT auction on playNomm for a pre-drop event of NFT Korea Festival. Artwork was sold out at its highest buyout price of US$22,128 in just one minute.SEOUL, KOREA, February 14, 2023 - (SEAPRWire) - On February 13th, on NFT marketplace playNomm (CEO, Sung-Uk Moon), Davey Perkins’, one of Superchief Gallery NFT artists, NFT has been sold out as soon as the auction started. The piece was bought out with the artists’ all-time high price. The artwork, 'We_R: 01', was sold for 49,483LM, equivalent of US$22,128. Davey Perkins is a freelance illustrator in Germany, who focuses on character design with a sci-fi concept. This February drop of 'We_R: 01' was an animated sci-fi illustration of a lost young pioneer, which expresses his unique style very well.As a pre-event of the NFT Korea Festival, three NFT auction events were held on playNomm NFT marketplace. The 1st drop was Shavonne Wong's 'Light in the Shadow' which was sold for 65,800LM, equivalent of US$26,776, the 2nd drop of Equinoz's 'Cybernetics', sold for 40,120 LM, equivalent of US$16,937, and finally, the last drop of Davey Perkins' 'We_R: 01', which recorded the fastest sold-out.The NFT Korea Festival is an event being held on Ma...

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MHIEC Builds a New Waste-to-Energy Plant with 194 Tons Per Day-Capacity in Konan City, Aichi Prefecture, Japan

ruth
4 minutes

TOKYO, Feb 14, 2023 - (JCN Newswire via SEAPRWire.com) - Mitsubishi Heavy Industries Environmental & Chemical Engineering Co., Ltd. (MHIEC), a Group company of Mitsubishi Heavy Industries, Ltd. (MHI), has received an order from the Owarihokubu Waste Disposal Association for building, operation, and maintenance of a new waste-to-energy plant. The association was established to consolidate waste treatment services of four municipalities in the northern Aichi region: Inuyama City, Konan City, Oguchi Town, and Fuso Town in Niwa County. The order calls for construction of an integrated waste-to-energy plant equipped with two stoker-type incinerators(1) collectively capable of processing 194 tons per day (tpd) in Konan City, to replace two superannuated plants in the association's service area. The operation startup is scheduled for April 2028.New Waste-to-Energy Plant of the Owarihokubu Waste Disposal Association (Rendering)Consolidating the services of four municipalities, the new plant will replace two superannuated facilities: Inuyama Waste Disposal Center (capacity: 135 tpd; designed and built by MHI; located in Inuyama City and operated since 1983) and Konan-Niwa Waste Disposal...

EQS Newswire

和铂医药与Cullinan Oncology就B7H4x4-1BB双特异性抗体签订授权及合作协议

eqs
1 minute

EQS 新闻 via SEAPRWire.com / 2023-02-14 / 11:12 UTC+8 和铂医药与Cullinan Oncology就B7H4x4-1BB双特异性抗体签订授权及合作协议 HBM7008是一款针对B7H4x4-1BB的双特异性抗体，由和铂医药创新的免疫细胞衔接器HBICE®平台开发 和铂医药将获得2500万美元预付款和最高达6亿美元里程碑付款，以及最高近20%销售额百分比的分级特许使用权费 和铂医药保留美国地区以外HBM7008的所有权利，以此为前提，Cullinan Oncology亦有权在欧盟或澳大利亚进行人体临床研究，并与和铂医药共享相关临床资料 和铂医药（股票代码：02142.HK）今日宣布与Cullinan Oncology, Inc.（纳斯达克：CGEM）签订授权及合作协议，授予Cullinan Oncology在美国（包括哥伦比亚特区和波多黎各）开发及商业化HBM7008（Cullinan Oncology产品代号为CLN-418）的独家许可权。HBM7008是一款针对B7H4x4-1BB的双特异性抗体，由和铂医药创新的免疫细胞衔接器HBICE®平台开发，目前正处于I期临床开发阶段。 根据协议，和铂医药将获得2500万美元预付款和最高达6亿美元里程碑付款，以及最高近20%销售额百分比的分级特许使用权费。Cullinan Oncology将承担在美国地区开发及商业化HBM7008的所有费用，和铂医药保留美国地区以外HBM7008的所有权利。此外，Cullinan Oncology亦有权在欧盟或澳大利亚进行人体临床研究（前提为和铂医药将保留HBM7008的所有权利）并与和铂医药共享相关临床资料。 和铂医药创始人、董事长兼首席执行官及HBMAT董事会主席王劲松博士表示：“此次合作是全球领先的合作伙伴对我们的技术平台和创新能力的又一次认可，也是和铂医药向这一潜在全球首创肿瘤免疫疗法迈出的坚实脚步。得益于其独特的肿瘤表达特异性和免疫调控活性，HBM7008表现出强大的抗肿瘤疗效，我们相信Cullinan Oncology是进一步开发HBM7008的最佳合作伙伴，他们拥有专业的临床开发团队、强大的肿瘤药物开发能力以及配套的设备资源。我们期待与Cullinan Oncology紧密合作将这个具有巨大潜力的创新产品全速推进。” Cullinan Oncology 首席执行官Nadim Ahmed先生表示：“我们很高兴将HBM7008（CLN-418）这款潜在全球首创且进入临床阶段的双特异性抗体引入Cullinan Oncology多元化的产品管线。B7H4是一种肿瘤相关抗原，在多种癌症中高表达，与PD-L1的表达重叠度极小，我们相信B7H4x4-1BB是针对B7H4的最佳通路之一。HBM7008的引进是Cullinan Oncol...

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KSTARDREAM launching, a K-POP platform where you can meet BTS and BLACKPINK

pandora
2 minutes

Seoul, Korea, February 14, 2023 - (SEAPRWire) - KSTARDREAM, a platform that allows you to check K-POP-related news the fastest and most accurately, was launched in February.KSTARDREAM is a multi-platform that allows you to quickly check K-POP-related news and use community activities, shopping, and live commerce with one ID.In addition, various K-pop singers' goods can be purchased as points generated through platform activities.KSTARDREAM plans to provide merchandise that cannot be purchased overseas for its members and create contents of K-POP stars that can only be used by members of KSTARDREAM, and KSTARDREAM's own K-POP concert will be held later to meet various singers such as BTS and BLACKPINK.An official from KSTARDREAM said, "We ask for your anticipation and interest in KSTARDREAM, a K-POP platform created by Koreans, not allkpop or reddit."Details of the KSTARDREAM platform can be found on the representative website, and free points that can be used immediately as a launching event are provided. Media ContactCompany: DREAMAGAINContact: BAE SANG INEmail: ceo@kstardream.comWebsite: https://kstardream.com/ SOURCE: DREAMAGAIN The article is provided by a third-party content p...

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MEV Capital Partners with Marex Solutions to Offer On-chain Structured Products in DeFi

pandora
3 minutes

London, the UK, February 13, 2023 - (SEAPRWire) - MEV Capital, a leading digital asset manager specializing in capturing value in the DeFi markets, and Marex Solutions, a renowned commodity broker and provider of OTC hedging solutions, announced their partnership to innovate and create new digital asset products.With MEV Capital's proficiency in DeFi and Marex's established reputation in the commodity markets, this collaboration is poised to pioneer novel and exciting opportunities for clients looking to diversify their portfolios and capitalize on the cryptocurrency industry.Harry Benchimol, Co-Head of Derivatives Engine at Marex Solutions, said, “We are thrilled to partner with MEV Capital and leverage their unique insight and market-neutral strategies in the DeFi space to provide a valuable offering to our clients. Manufacturing innovative derivatives with MEV Capital's expertise will allow both parties to create new products combining the best centralized and decentralized finance.”MEV Capital has been a prominent player in the DeFi space, specializing in on-chain yield strategies such as liquidity provision, statistical arbitrage, and carry trading. Their extensive experience ...

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Honda Motor Co-founder Takeo Fujisawa to be Inducted into Automotive Hall of Fame

ruth
4 minutes

Detroit, Michigan, Feb 13, 2023 - (JCN Newswire via SEAPRWire.com) - Takeo Fujisawa, co-founder of the Honda Motor Co., Ltd., will be inducted into the Automotive Hall of Fame at its awards ceremony at The Fillmore Detroit on July 20. Fujisawa will join Honda founder Soichiro Honda, who was inducted in 1989 as the first Japanese automotive executive honored by the Automotive Hall of Fame, located in Dearborn, Michigan. Born on November 10, 1910, Fujisawa originally aspired to become a teacher, but instead worked as a salesman for a steel products company and then for a lumber company when he met Soichiro Honda in August 1949, about one year after the founding of Honda Motor Co., a small local venture in Hamamatsu, Japan. It was the right after the launch of the Dream D-Type, considered to be Honda's first full-fledged motorcycle product. While the two men were equipped with different personalities and skill sets, Honda and Fujisawa hit it off almost immediately and began deep discussions about their approach to business and dreams for the future. Quickly developing a trusting relationship, they established a shared vision for the future of the company with Fujisawa joining Honda Mo...

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医思健康与保诚香港达成战略合作

tallulah
1 minute

HONG KONG, Feb 13, 2023 - (亚太商讯 via SEAPRWire.com) - 香港最大非医院医疗服务机构*──医思健康（「公司」，连同附属公司，总称「集团」；香港联交所股份编号：2138）欣然宣布，集团与保诚保险有限公司（「保诚」）达成战略合作关系，双方将共同开发定制化的健康管理增值服务，守护客户的健康及财富。基于双方的战略合作，医思健康将作为专属服务供应商，向保诚的客户提供复必泰二价疫苗注射及其他医疗服务，保诚香港客户可透过网上平台进行预约。医思健康致力构建一站式多专科大健康服务闭环平台，与保险巨头的合作是公司核心策略的重要组成部分。得益于多年来建立的领先品牌及透过独特的一站式大健康生态提供的全面健康管理服务，集团与保险巨头建立了互信的合作关系，不断完善可实现产业链纵深整合的大健康闭环生态系统。秉承同样「以客为本」的理念，集团与保诚香港达成战略合作，为客户提供可持续，可负担，可触达的优质的预防性及精准性之医疗服务。医思健康执行董事兼联席行政总裁吕联炜先生表示︰「集团非常荣幸能够与香港领先且具有悠久历史的保险产品供应商保诚达成战略合作，为更广泛的客户提供优质且多样化的健康管理服务。香港私营医疗市场具有巨大潜力，集团相信是次合作将可促进保险公域客户引流，加速集团于医疗健康服务的内生增长。未来集团持续推进与科技、电讯、保险、房地产及制药领域企业的深度战略合作，不断完善医思闭环大健康生态系统。」保诚保险有限公司行政总裁林智刚先生表示：「对保诚而言，我们了解每一位客户都是独一无二，各有不同的人生目标和梦想追求。通过与医思健康等行业龙头携手合作，我们致力为客户提供适时的健康和财务保障，协助他们于身心健康的旅程上取得成功，活出精彩人生。」关于医思健康香港最大非医院医疗服务供应商*医思健康以预防及精准医疗为业务核心，透过多元服务整合发展医疗人工智慧，配套高端品牌及优质客户服务，致力为客户提供最专业、安全、有效的医疗健康服务。集团为恒生综合指数成份股及MSCI香港小型股指数。集团目前直营的诊所／服务中心主要位于大湾区，提供一站式医疗及健康服务。服务涵盖面极广，旗下主要知名服务品牌包括连续多年荣膺全港第一的一站式医学美容解决方案DR REBORN、专业健发中心发森及多元化多维度的医学服务包括：健康管理中心香港仁和体检中心、疫苗中心香港安苗医疗中心、普通科门诊未来医生、全港最大一站式痛症管理平台纽约脊骨物理治疗中心、全方位牙科服务中心庇利积臣牙科医务所，EC DENTAL CARE及恒健牙科医务所、高端影像中心博思医学诊断中心、仁生肿瘤及癌症中心、内视镜及日间医疗中心仁辉专科中心、专科中心进汇医务中心，联汇专科，新医疗中心、儿科专科汇儿儿科医务中心、妇产科专科卓越医务中心及产前诊断中心、柏立医学化验所、眼科中心唯视眼科和医思兽医医院及影像中心。*根据...

ACN Newswire
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EC Healthcare Announced Strategic Alliance with Prudential

indie
4 minutes

HONG KONG, Feb 13, 2023 - (ACN Newswire via SEAPRWire.com) - EC Healthcare (the "Company", which together with its subsidiaries is referred to as the "Group", SEHK stock code: 2138), the largest non-hospital medical group in Hong Kong*, is pleased to announce that the Group formed partnership with Prudential Hong Kong Limited ("Prudential") to jointly offer tailored and value-added healthcare services, enabling customers to achieve their health and wealth ambition. Through this partnership, customers of Prudential can enjoy exclusive offer on bivalent vaccination service provided by EC Healthcare via online reservation platform, amongst many other healthcare services.EC Healthcare has been developing a one-stop, multi-disciplinary, enclosed healthcare service platform and positioning strategic collaboration with insurance giants as a crucial part of the Group's core strategy. Benefiting from the long-stand leading brand and the comprehensive healthcare services provided under the unique one-stop healthcare ecosystem, the Group formed a strategic partnership with Prudential based on mutual trust, further enriching the Group's vertically integrated healthcare ecosystem. With the shar...

JCN Newswire
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JCB Reaches One Million Rupay JCB Card Issuance Mark in India

ruth
3 minutes

TOKYO, Feb 13, 2023 - (JCN Newswire via SEAPRWire.com) - JCB International Co., Ltd., the international operations subsidiary of JCB Co., Ltd., Japan's only international payment brand, today announced issuance of one million Rupay JCB Cards in India. These credit and debit cards, issued by 12 public and private sector banks and co-badged as RuPay JCB Cards, offer their cardmembers a seamless payment experience within and outside India.Along with the 3-fold growth in card issuance, a significant growth in Rupay JCB Card usage was also seen with international spending growing 8-fold between April 2022 to December 2022. This is expected to further grow rapidly given the extremely lucrative international campaign currently available for RuPay JCB cardmembers. All RuPay JCB cardmembers are eligible for a whopping 40% cashback on face-to-face transactions in Singapore, Thailand and Bahrain. The maximum cashback amount per transaction is 3,000 INR and maximum cashback amount per one card is 15,000 INR within the campaign period. The current campaign started on December 29, 2022 and will conclude on March 31, 2023.This is the second such campaign as RuPay JCB just concluded a similar 40% ...

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NEC successfully demonstrated Multi-Vendor Near-RT RIC Integration in O-RAN Global PlugFest 2022

ruth
3 minutes

TOKYO, Feb 13, 2023 - (JCN Newswire via SEAPRWire.com) - NEC Corporation (TSE: 6701) successfully demonstrated multi-vendor integration and interoperability of a Near-Real-Time RAN Intelligent Controller (Near-RT RIC) at the new windowO-RAN ALLIANCE Global PlugFest Fall 2022 in Japan.Roadmap for RIC DevelopmentNEC, VIAVI Solutions and HCL Technologies (HCLTech) teamed up for this project to demonstrate the multi-vendor Near-Real-Time RIC performance benchmarking. NEC's Near-RT RIC platform enabled third party xApp integrations while connecting with multi-vendor E2 nodes.RIC reduces RAN operating costs by automatically configuring base stations and optimizing radio parameters leveraging AI. Near-RT RIC enables advanced control for Quality of Service (QoS) in near real-time on a per-user basis, and in conjunction with Service Management and Orchestration (SMO)/ Non-Real-Time RIC, achieves an optimal balance between RAN operating costs and QoS/ Quality of Experience (QoE). The entire vRAN system will be optimized for various services and requirements in the future by coordinating the control of radio resources and computing resources through RIC.For this PlugFest project, HCLTech's Bo...

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Blockchain Life will host the 10th Global Blockchain and Crypto Forum in Dubai

indie
2 minutes

DUBAI, Feb 13, 2023 - (ACN Newswire via SEAPRWire.com) - The 10th Global Forum on blockchain, cryptocurrencies and mining -- Blockchain Life 2023 takes place on February 27-28 in Dubai. The event is attended by key industry players, government representatives, heads of international companies and funds, investors, promising startups teams and beginners. It's noteworthy that the Forum is a meeting point for a premium crypto audience including world Crypto Whales.What to expect?- Whales of the crypto industry at one place- Top speakers with world-changing insights and analytics - Global expo of the latest Web 3.0 technologies- Breakthrough smart networking app- The legendary AfterParty on the luxury yacht trip Top speakers:- Yat Siu - Co-Founder and Executive Chairman of Animoca Brands, Founder and CEO of Outblaze- Sergei Khitrov - Founder of Listing.Help and Jets.Capital- Ben Zhou - Co-founder and CEO of Bybit- Dr. Marwan Alzarouni - CEO of Dubai Blockchain Center- Carl Runefelt - Crypto Entrepreneur, Founder Of CryptoJobs.com- Chris MMCrypto - Cryptocurrency Expert, Co-Founder of MMCrypto- Gabriel Abed - Ambassador of Barbados to the UAE- Dr. Mohamed Al Hemairy - Director of Techno...

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Novotech 全球报告：亚太地区稳健的 1 期试验增长

tallulah
1 minute

SYDNEY, AU, Feb 13, 2023 - (亚太商讯 via SEAPRWire.com) - 以亚太地区为中心的领先生物技术 CRO Novotech 发布了一份关于 Phase 1 试验活动的新全球报告，包括快速增长区域和治疗领域的当前指标。 数据分析发现，亚太地区是过去十年中 1 期试验增长最快的地区，到 2022 年达到 58% 的份额，其中中国在全球领先 1 期试验。Novotech 在欧洲和美国提供独特且无与伦比的早期至晚期 CRO 服务套件，并专注于亚太地区，该公司在提供高质量的快速临床试验方面享有盛誉。根据题为“I期全球临床试验格局——聚焦亚太地区”的新报告，2022 年亚太地区占全球启动的约 3,600 项 I 期试验的 58%。 该报告发现，亚太地区是过去十年中 1 期试验增长最快的地区，10 年复合年增长率为 18%。 2018年至2022年间，该地区表现稳定，自2018年以来一直保持多数份额，2021年达到61%的峰值。中国大陆、澳大利亚、韩国、日本和印度是亚洲前五名 地点，共同贡献了全球 I 期试验的 50% 以上。亚太地区有需求的关键原因之一是它拥有最短的患者入组时间和最快的招募速度。 亚太地区拥有更广泛的患者基础，这加快了患者招募过程并缩短了试验持续时间，从而能够启动和完成试验。该报告发现，亚太地区还领先于顶级治疗领域的 I 期试验。 肿瘤、传染病、中枢神经系统、心血管和代谢紊乱是中国、澳大利亚、韩国、日本和印度等亚洲主要地区进行 I 期试验的主要治疗领域。 在所有五个地点的总和中，中国在所有综合考虑的顶级治疗领域的 I 期试验中占据了主要份额（>80%）。”请参阅第 1 阶段位置和治疗区域分析的 报告，包括：- 免疫调节疗法- 免疫肿瘤学- 过继细胞疗法- 同种异体、自体、干细胞和再生医学- DNA 和 RNA- 疫苗- 多特异性单克隆抗体- 微生物组细胞与基因最新数据还显示，亚太地区是全球细胞和基因治疗试验增长最快的地区，占所有细胞和基因研究的三分之一以上，其中中国在该地区处于领先地位。 2016 年至 2021 年，该地区已经占细胞和基因治疗试验活动的三分之一以上，并且与世界其他地区相比，细胞和基因治疗试验的增长率快了近 50%。中国的增长率比世界其他地区快 15%。 在肿瘤学之后，大多数细胞和基因试验都在传染病、中枢神经系统和心血管疾病中进行。 此外，亚太地区是全球 CAR-T 试验的领先地区，2015 年至 2022 年间，中国吸引了全球约 60% 的 CAR-T 试验。欧洲扩张——全球足迹该公司最近收购了 EastHORN，这是一家欧洲 CRO，在欧洲大陆多个具有重要战略意义的地点拥有临床、医疗和监管专业知识。 此次收购是 Novotech 在欧洲和美国的全球扩张计划的一部分。奖项表彰Novotec...

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Korindo Transfers Urban Forest Management to Bogor Regency Government

indie
3 minutes

Bogor, Indonesia, Feb 11, 2023 - (ACN Newswire via SEAPRWire.com) - After three years of planting and maintenance under Korindo Foundation's care, Pakansari Stadium's urban forest (or Pakansari City Forest) was finally handed over to the Bogor Regency Government at the beginning of February 2023. Rows of Eucalyptus deglupta trees green the areas of Pakansari City Forest in Cibinong, Bogor Regency (West Java, Indonesia) [Image: Korindo]Chairman of Korindo Foundation Robert Seung and Bogor acting regent Iwan Setiawan signed the handover plaque. [Image: Korindo]Korindo Foundation Chairman Robert Seung performed the handing-over ceremony with Bogor's acting regent Iwan Setiawan, the handover fulfilling the region's dream of owning a lush urban forest. Pakansari City Forest is, in fact, the first wooded area to be established in Bogor Regency."Through the Green Collaboration program, Korindo Group and Foundation are committed to supporting government efforts that keep our country's natural environment and our beloved Earth sustainable," said Robert Seung in his opening speech.This green space was actually a part of the regency government's masterplan, but for several reasons, its constr...

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First Patient in the US Dosed in a Global Multicentre Phase 3 Clinical Study of Bevacizumab for treatment of Ophthalmic Diseases

indie
6 minutes

HONG KONG, Feb 10, 2023 - (ACN Newswire via SEAPRWire.com) - Essex Bio-Technology Ltd ("Essex" or the "Group", Stock Code: 1061.HK) today announced that the first patient in the United States (US) was dosed in a global multi-centre phase 3 clinical trial (NCT04740671) of EB12-20145P (HLX04-O), a recombinant anti-VEGF humanised monoclonal antibody injection jointly developed by the Group and Shanghai Henlius Biotech, Inc. ("Henlius", Stock Code: 2696.HK), for the treatment of wet age-related macular degeneration (wAMD). Previously, the first patients in the European Union (EU) and Australia were dosed in the same global multicenter phase 3 clinical trial of EB12-20145P (HLX04-O). Meanwhile, the first patient has been dosed in a parallel phase 3 clinical trial in China for EB12-20145P (HLX04-O) for the treatment of wAMD.This randomised, double-blinded, active-controlled, global phase 3 study aims to compare the efficacy and safety of EB12-20145P (HLX04-O) with ranibizumab in patients with wet age-related macular degeneration (wAMD). Eligible patients will be randomised 1:1 to receive intravitreal injection of EB12-20145P (HLX04-O) (1.25 mg) or ranibizumab (0.5 mg) every 4 weeks for 4...

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亿胜生物宣布贝伐珠单抗眼科适应症国际多中心III期临床研究完成美国首例患者给药

tallulah
3 minutes

HONG KONG, Feb 10, 2023 - (亚太商讯 via SEAPRWire.com) - 亿胜生物科技有限公司（“亿胜生物”或“集团”，股票代码：1061.HK）今日宣布，集团与上海复宏汉霖生物技术股份有限公司（“复宏汉霖”，股票代码：2696.HK）合作开发重组抗血管内皮生长因子（Vascular endothelial growth factor，VEGF）人源化单克隆抗体注射液EB12-20145P（HLX04-O）的国际多中心III期临床研究（NCT04740671）完成美国首例患者给药，拟用于湿性年龄相关性黄斑变性（wet age-related macular degeneration, wAMD）的治疗。该临床研究此前已在澳大利亚和欧盟完成首例患者给药。另一项在wAMD患者中开展的针对EB12-20145P（HLX04-O）的III期临床研究已于中国完成首例患者给药。该研究是一项在湿性年龄相关性黄斑变性（wAMD）患者中开展的旨在比较EB12-20145P（HLX04-O）与雷珠单抗的有效性和安全性的随机、双盲、阳性对照的全球III期研究。合格的受试者将以1:1的比例随机分为两组，分别于48周内每四周玻璃体腔内注射EB12-20145P（HLX04-O）（1.25 mg）或雷珠单抗（0.5mg）。其主要目的为比较第36周EB12-20145P（HLX04-O）与雷珠单抗在wAMD患者研究眼中的有效性，主要终点为第36周最佳矫正视力（Best corrected visual acuity，BCVA）较基线改善的平均字母数变化。次要目的包括评估其他疗效终点、安全性、耐受性以及药代动力学特征等。EB12-20145P（HLX04-O）是复宏汉霖利用基因工程技术构建的一款重组抗VEGF人源化单克隆抗体注射液，能够特异性结合血管内皮生长因子（VEGF），阻断VEGF与内皮细胞上的受体Flt1（VEGFR-1）和KDR（VEGFR-2）结合，抑制其酪氨酸激酶信号通路的激活，进而抑制内皮细胞增生，减少新生血管生成，从而实现对wAMD等血管增生性眼部疾病的治疗。根据眼科用药需求，在贝伐珠单抗汉贝泰®的基础上保持活性成分不变，对处方、包装材料、规格和生产工艺等进行优化，开发了新的眼科制剂产品EB12-20145P（HLX04-O）。可比性研究表明生产工艺和制剂处方的变更对药物制剂的质量、安全性和有效性未产生不利影响。除已完成首例患者给药的欧盟、澳大利亚及美国，EB12-20145P（HLX04-O）已获得包括新加坡在内的多个国家和地区的临床试验许可。亿胜生物携手复宏汉霖将持续推动EB12-20145P（HLX04-O）的国际多中心III期临床试验，以期凭借相关研究结果实现EB12-20145P（HLX04-O）在中国、澳大利亚、欧盟和美国等全球...

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XOX Strengthens Presence in Local Football Scene with KLCFC Partnership

indie
3 minutes

KUALA LUMPUR, Feb 10, 2023 - (ACN Newswire via SEAPRWire.com) - XOX Berhad (XOX), via its sports marketing arm, XOX Pro Sport Sdn. Bhd., and the Kuala Lumpur City Football Club (KLCFC) have kick-started a partnership to offer XOX's comprehensive range of product and service to the public. The companies in XOX's ecosystem range from technology offerings to financial products, events management and even apparels.Mr Winson Wong, Chief Operating Officer XOX; Mr. Ng Kok Heng, Group CEO XOX; Mr. Stanley Bernard, CEO of Kuala Lumpur City FC; Mr. Noor Azri bin Noor Azerai, Director of Rinani Group Berhad [L-R]Mr. Tan Tai Liang, Chief Sales Officer; Ms. Sylvia Kong Choo Hui, Group Chief Financial Officer XOX; Mr. Yakub Hussaini, General Manager Kuala Lumpur City FC; Mr. Winson Wong, Chief Operating Officer XOX; Mr. Ng Kok Heng, Group CEO XOX, Mr. Stanley Bernard, Chief Executive Officer Kuala Lumpur, Mr. Noor Azri Bin Noor Azerai, Director of Rinani Group Berhad [L-R]The initial collaborative products to be rolled out are multiple co-branded mobile plans by another of XOX's subsidiary, ONEXOX Sdn Bhd, which are targeted at KLCFC's avid supporters. Fans of the football club who subscribe to ...

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Bintai Kinden Wins RM14.2 Million Project from TNB

indie
2 minutes

PETALING JAYA, Malaysia, Feb 10, 2023 - (ACN Newswire via SEAPRWire.com) - Bintai Kinden Corporation Bhd (Bursa: BINTAI, 6998), a mechanical and electrical (M&E) engineering services specialist, is pleased to announce that the Company's wholly-owned subsidiary, Kejuruteraan Bintai Kindenko Sdn Bhd (KBK), has been awarded a project worth RM14.2 million by Tenaga Nasional Berhad (TNB) for the installation of two 132kV transformer bays air insulated switchgear complete with the relevant primary, secondary, cables and all associated civil works located in Pasir Besar, Negeri Sembilan.Executive Director of Bintai Kinden, En. Azri AzeraiThe project's scope of work also includes a 33kV building, two 300kVA 33/0.415kV local transformers, 33kV GIS single busbar (eight outgoing, two incomer, two local transformers and two bus-ties), 33kV CRP, 33kV RTU, 33kV SIP and 33kV MPE, neutral earthing system, earthing system extension, lightning protection system, associated secondary works (protection & telecontrol) and, associated underground cable works for power transformer, local transformer and bus-tie.KBK, a specialist in M&E engineering services, was also awarded a project worth RM...

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百果园年货节成绩亮眼：全渠道终端零售额超13亿元，三四线市场消费升级明显

tallulah
1 minute

HONG KONG, Feb 10, 2023 - (亚太商讯 via SEAPRWire.com) - 每年春节前后，各大商家都会围绕年货进行营销，国内水果连锁零售龙头企业百果园，也一直坚持“春节不打烊”传统，水果蔬菜备货充足，全面满足消费者春节期间的饮食和送礼需求。据悉，百果园年货节（2023年1月3日至2月5日）期间，全渠道终端零售额超过13亿元。与往年春节不同的是，随着2022年底疫情管控放开，国人返乡热情高涨，今年春节送礼需求增势明显。百果园年货节期间，水果礼盒装总销量超134万个，贡献金额超3亿元，同比增长 21.4%。三四线下沉市场数据表现尤为突出：年货节期间，百果园销售TOP10城市中，三四线城市占据约60%。为了满足消费者更便捷、更个性化地购买，百果园针对顾客需求定制了不同的春节礼盒装，如单品礼盒、成品礼盒、小件购、组装礼盒等，并在百果园全渠道上架销售。消费者可以通过门店、百果园App上的及时达和次日达商城、百果园微信小程序以及三方渠道（饿了么、京东、口碑拼团、美团点评、美团外卖）等渠道下单。在年货节的水果销售TOP榜单中，进口车厘子名列第一，成消费者最喜爱水果，仅百果园B2C渠道，销售额同比增长约33%。此外草莓、蜜瓜、苹果、柑橘等水果，也因好吃及好寓意成为春节热销果品。“好吃”是百果园的品牌战略，也是百果园的核心价值。这几年春节，百果园针对好吃，持续推出“把好吃带回家”营销。今年，由百果园营销团队策划并拍摄制作的“把好吃带回家”暖心视频，聚焦疫情后的烟火气息，随机采访小摊贩以及路人，就2022年以及回家等话题讲述感受，引发大家对家乡的思念，对“好吃”的美好回忆。视频在百果园新媒体渠道发布后，触动了无数网友，截至目前该视频总曝光量近500万。果品层面，百果园针对自有品牌红芭蕾草莓、王品山地橙及车厘子等春节热销的好吃水果，做了系列营销活动。以品牌联动、话题打造，以及抖音直播、抖音团购带货等形式持续拓宽果品销路，实现品效合一。数据显示，截至目前#百果园车厘子话题整体曝光达2339万，针对车厘子策划的主题#点亮团圆的红 话题曝光量达1881万。百果园自有品牌红芭蕾草莓也成为抖音渠道的人气单品，#百果园草莓#话题曝光量达1345万，其中红芭蕾草莓整体曝光量超过800万。百果园相关人士表示，基于红芭蕾已经逐渐占据顾客心智，2022至2023销售季，红芭蕾草莓的铺货量将有较大增加。这是百果园在港交所主板挂牌上市后的第一个春节，作为一家公众公司，百果园将更加注重消费者体验，为消费者提供好吃果品的同时，带来更好的服务体验。（来源：互联网） Copyright 2023 亚太商讯. All rights reserved. (via SEAPRWire)