TOKYO, Mar 16, 2021 - (JCN Newswire via SEAPRWire.com) - Eisai Co., Ltd. announced today that anti-microtubule binding region (MTBR) tau antibody E2814, which was created from collaboration research between Eisai and University College London, has been selected by the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) led by Washington University School of Medicine in St. Louis, as the first investigational medicine among anti-tau drugs for their DIAN-TU tau study.People who have a genetic mutation of dominantly inherited Alzheimer's disease (DIAD); nearly certain to develop Alzheimer's disease (AD), tend to develop symptoms at around the same age their affected parents did, often in their 50s, 40s or even 30s. DIAN-TU launched in 2012 as the first prevention trial for DIAD using anti amyloid-beta (Ab) drugs. Amyloid plaque that consists of Abeta aggregates, as well as neurofibrillary tangles, one of the major AD pathologies, are intraneuronal aggregates of tau and they are believed to spread throughout the brain. The DIAN-TU tau next-generation program will evaluate three anti-tau drugs in clinical studies and has selected E2814 as the first investigational anti-tau drug...