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DZNE and Eisai Enter Into Research Collaboration Agreement Aiming for Novel Drug Discovery for Neurodegenerative Disorders

ruth 17 3 月

3 minutes

TOKYO, Mar 17, 2021 - (JCN Newswire via SEAPRWire.com) - Deutsches Zentrum fur Neurodegenerative Erkrankungen and Eisai Co., Ltd. today announced that both parties have entered into a research collaboration agreement aiming to create potential novel treatments for neurodegenerative disorders including Alzheimer's disease (AD) which modulate immune competence in neurons and glia cells.DZNE is a world-leading interdisciplinary public research organization constituted with ten research sites in Germany that investigates methods for prevention, diagnosis and treatment against neurodegenerative diseases. The collaboration will incorporate DZNE's expertise in the fundamental and clinical research with Eisai's abundant experience in drug discovery for neurodegenerative diseases to accelerate development of novel drug candidates.Prof. Pierluigi Nicotera, Chairman of the DZNE's Executive Board commented: "We are pleased to have formed this collaboration with Eisai, which has an outstanding track record and a company-wide commitment to providing innovative treatments in the neurodegenerative disorders field. We think that this collaboration will be able to accelerate creation of new treatmen...

Hong Kong bankers work around the clock as IPOs, Spacs surge

elean 17 3 月

5 minutes

HONG KONG (BLOOMBERG) - Hong Kong's bankers are working around the clock as the region's companies rush to go public. Initial public offerings in the city have already hit almost US$11 billion (S$14.8billion), a close to 500 per cent jump from a year earlier, with video streaming platform Bilibili and search giant Baidu among companies preparing multi-billion dollar deals. Digital roadshows and clients eager to move faster to capture abundant liquidity - especially as market sentiment has begun to sour - means bankers are keeping dawn-to-midnight schedules, say some, even turning down deals where they're relegated to junior roles. Companies are trying to "get the deal done as soon as they can," said Stephanie Tang, head of private equity for greater China at Hogan Lovells. "Many of them see this as an opportunity and if they are not catching the train quickly, they might lose the opportunity." A pandemic-induced hunger for technology stocks and the threat of US delistings have been a boon for the financial hub during a difficult political stretch, driving a surge in initial and secondary share sales. A new push by Shanghai's Nasdaq-like Star board to more closely scrutinize IPOs al...

Singapore start-up PatSnap turns unicorn with backing from SoftBank, Tencent

elean 17 3 月

3 minutes

SINGAPORE (BLOOMBERG) - Singapore-founded PatSnap reached a valuation topping US$1 billion (S$1.34 billion) in a fresh funding round, with SoftBank Vision Fund II and Tencent Investment among those backing the provider of patent analytics. CPE Industrial Fund and existing investors Sequoia China, Shunwei Capital and Vertex Ventures joined the US$300 million Series E round, the software company said in a statement. PatSnap will use the funds for product development and expanding its sales presence. Joining the list of global technology unicorns, PatSnap is benefiting from a surge in R&D spending, with the US and China seeking an edge amid heightened trade tensions between the countries. PatSnap's software lets inventors and researchers gain insights into innovations being developed around the world. "The US-China trade war is essentially about technology and a lot of companies want to know where to invest," Jeffrey Tiong, PatSnap founder and chief executive officer, said in an interview. "We spent more than 10 years collecting patent data from 140 countries and use AI to provide insights." Founded in 2007, PatSnap - short for patents in a snap - provides data and analytics on intell...

Uber grants UK drivers worker status in world first

elean 17 3 月

3 minutes

LONDON (AFP) - Uber on Tuesday (March 16) said it is granting its UK drivers worker status, with benefits including a minimum wage - a world first for the US ride-hailing giant. Weeks after a top court ruling that could shake up Britain's wider "gig economy" of 5.5 million people, Uber said its drivers would also get holiday pay and a pension. It is a massive change in the business model of a company that had argued before Britain's Supreme Court that its drivers were self-employed. From Wednesday, "more than 70,000 drivers in the UK will be treated as workers, earning at least the national living wage when driving with Uber," the taxi app said in a statement. "This is a floor and not a ceiling, with drivers able to earn more." The court ruled last month that Uber's drivers are entitled to worker's rights. The decision capped a protracted legal battle between UK drivers and the Silicon Valley taxi and delivery company. 'Flexibility Remains' Uber said its action over workers' rights "means drivers will earn with greater security, helping them to plan for their futures while maintaining the flexibility that is integral to the private-hire industry." The higher costs for Uber come as ...

Moonstake Partners with Hybrid Enterprise-Grade Blockchain Orbs to Soon Provide Full-Scale Support for Orbs Universe

indie 16 3 月

4 minutes

SINGAPORE, Mar 16, 2021 - (ACN Newswire via SEAPRWire.com) - Moonstake announces today that it has signed an MOU with Orbs, a hybrid blockchain infrastructure with enterprise-grade scale, security, and support.Through this collaboration, Moonstake will soon support the staking of ORBS, Orbs' official token, on Moonstake Wallet, as well as participate further in the Orbs blockchain ecosystem. The two parties will also host community building programs, research, training, events, and conferences with the goal to increase awareness and adoption of Blockchain and Distributed Ledger Technology in the Banking and Finance Industry. Moonstake and Orbs will discuss further potential provision of consulting services to financial institutions in the regions of Southeast Asia and Middle East.Moonstake started in the staking business last year with the aim to create the largest staking network in Asia. Since then, Moonstake has developed the most user-friendly wallets for both Web Wallet and Mobile Wallet (iOS/Android) that are compatible with over 2000 cryptocurrencies. After a full-scale operation launched in August 2020, Moonstake's total staking assets have grown rapidly to reach USD 800 Mi...

National Council of Social Service launches guide for media reporting on mental health issues

aseanpr 16 3 月

4 minutes

SINGAPORE - As part of efforts to address the stigma associated with mental health conditions, the National Council of Social Service (NCSS) on Tuesday (March 16) launched a guide with words and phrases that should be avoided when reporting on the issue. For example, the phrase "someone with a mental health condition" is preferred over terms such as "mentally ill", "psycho", "mad" or "crazy". Aside from stigmatising terms and their suggested alternatives, the Beyond the Label Media Guide contains suggestions on how people with mental health conditions should be interviewed, as well as angling and headlining stories, and reporting on violence and suicides. The guide was developed in consultation with social service agencies, mental health professionals, persons with mental health conditions and members of local media. Ms Anita Fam, president of NCSS, said the guide provides recommendations for media professionals reporting on mental health issues or writing about incidents involving persons with mental health conditions. "We believe that the media is and can be instrumental in influencing and changing attitudes and behaviour, educating and encouraging people to think differently abo...

New SafeEntry system lets you tap phone or TraceTogether token on gateway box to check in

aseanpr 16 3 月

6 minutes

SINGAPORE - The SafeEntry check in to public venues will become a simpler and faster process from April 19 with a new tap-in system. The new SafeEntry Gateway Box was launched on Tuesday (March 16) at Nex mall in Serangoon Central by the Smart Nation and Digital Government Office (SNDGO). It was trialled at the mall from Feb 15. To check in, visitors with the TraceTogether app or TraceTogether tokens can tap their devices on the gateway box, which is slightly larger than a smartphone. Alternatively, an operator of a venue, such as a supermarket or large shop, can download an updated version of the SafeEntry (Business) App on his phone and use the phone, instead of the gateway box, for visitor check ins. The SafeEntry Gateway system is being planned for a rollout at selected crowded venues such as shopping malls, large standalone retail stores, cinemas, hospitals, polyclinics and Mice (meetings, incentives, conferencing and exhibitions) venues hosting more than 100 participants. Existing SafeEntry check-in methods using the QR codes and a visitor's NRIC will still be used at these places. The Government has identified venues with high visitor traffic that need to implement the SafeE...

Crypto exchange BitMEX founder surrenders to face money laundering charges

elean 16 3 月

2 minutes

NEW YORK (BLOOMBERG) - One of the founders of pioneering crypto-derivatives exchange BitMEX surrendered to authorities to face charges that he schemed to avoid US anti-money laundering laws. Benjamin Delo, who traveled to New York from the UK, was arraigned before US Magistrate Judge Sarah L. Cave during a remote proceeding on Monday (March 15). He pleaded not guilty and was released on a US$20 million (S$26.9 million) bail bond. The terms of his bail allow him to return to the UK. An Oxford-educated computer scientist who previously created high-frequency trading systems for JPMorgan Chase & Co, Delo founded BitMEX with Arthur Hayes and Samuel Reed in 2014. Once the world's largest crypto-derivatives exchange, Bitmex invented perpetual Bitcoin futures that were easy for retail investors to understand and gained popularity for letting investors leverage their bets. All three were charged in October by federal prosecutors in New York with flouting banking laws while serving US customers. The government said the executives ignored requirements that it register with the Commodity Futures Trading Commission and set up programs to make sure it wasn't used for illegal purposes. "The char...

China plans new food trading giant with Cofco merger and IPO

elean 16 3 月

3 minutes

BEIJING (BLOOMBERG) - China's largest food company plans to merge its international trading division with several domestic businesses to create a new agricultural commodity behemoth before embarking on an initial public offering. Cofco Corp has hired bankers to advise on a plan to combine Cofco International with some of its domestic trading and processing assets, according to people familiar with the talks. After the merger, Cofco plans to sell shares in the new company, most likely in Shanghai, the people said, asking not to be named as the matter is private. The IPO could value the new company at more than US$5 billion (S$6.7 billion), the people said. The combination will create a new agricultural trading giant, putting Cofco's international trading unit and some of its domestic businesses under one umbrella, with assets spanning Brazil to China, the people said. The new company will compete with the so-called ABCDs, a quartet of global traders which have dominated the industry for decades: Archer-Daniels-Midland, Bunge, Cargill and Louis Dreyfus. China, the world's largest buyer of commodities, has helped drive food prices higher over the past 12 months with record purchases o...

Strategists see upside for equities from broad economic rebound

elean 15 3 月

4 minutes

SINGAPORE - Market turbulence continued through last week with sentiment swinging between euphoria over potential economic recovery and fear over inflation. United States President Joe Biden's US$1.9 trillion (S$2.6 trillion) Covid-19 rescue package fuelled hopes of supercharging the economic recovery, while also stirring up concerns that adding more liquidity to a system already floating on some US$4 trillion of cash could further add to inflationary pressures. Treasury yields, especially that of the 10-year bond, continued to trend upwards, testing the key 1.6 per cent levels. The number of people making initial claims for jobless benefits fell the previous week to its lowest level since the pandemic, but US consumer prices rose by just 0.4 per cent last month, in line with expectations. Despite inflation concerns, most market strategists see an upside for the equity market in the foreseeable future, largely supported by a broad economic recovery. Here is how BlackRock put it last week: "Nominal yields have been climbing since September, but the magnitude has lagged that of the rise in inflation expectations during the period. Inflation-adjusted yields remain deep in negative ter...

Recharging Asean’s approach to climate transition

elean 15 3 月

1 minute

SINGAPORE - Covid-19 has had a devastating toll on Asean economies but it's easy to forget that another crisis looms - climate change - to which the region is deeply vulnerable. While all Asean members have made Paris pledges, implementation has not been easy with huge infrastructure and funding gaps. If nothing is done, the economic impact of climate change will be profound - estimated GDP per capita loss for Asean members range from 0.7 per cent to 8.5 per cent by 2100. And this doesn't even take into account societal or environmental impacts. Please subscribe or log in to continue reading the full article. Get unlimited access to all stories at $0.99/month Latest headlines and exclusive stories In-depth analyses and award-winning multimedia content Get access to all with our no-contract promotional package at only $0.99/month for the first 3 months* Subscribe now *Terms and conditions apply.

Not possible for S’pore, many countries, to choose between US and China, PM Lee tells BBC

aseanpr 14 3 月

6 minutes

SINGAPORE - It will not be possible for Singapore to choose between the United States and China, given the extensive ties the Republic has with both superpowers, said Prime Minister Lee Hsien Loong on Sunday (March 14). Many other countries are in a similar situation, he added during an interview with the BBC, saying they would be hard pressed if forced to pick a side. "I hope the time does not come," he said when asked which one Singapore will choose when the time comes. "I do not think this is a dilemma only for Singapore. It is a problem for many countries, which is why we are all hoping and encouraging the two large powers to think very carefully before deciding that the other one is an adversary which has to be kept down, if not put down." The past few years have seen a significant deterioration in ties between the US and China, with their rivalry set to continue in spite of the change in administration in Washington. With both sides exerting their influence on allies and partners, it has become harder for countries to stay in the middle. The administration of US President Joe Biden, for instance, has called for a review of how the country buys strategic goods, saying that it ...

Me & My Money: Spending within his means and being cautious help him grow his business and finances

elean 14 3 月

1 minute

SINGAPORE - Business owner Desmond Tay believes in keeping it simple when it comes to personal finance - spend within your means and do not over-leverage. Its an approach that he extends to running his firm, with risks carefully calculated and financial outlays made cautiously. Please subscribe or log in to continue reading the full article. Get unlimited access to all stories at $0.99/month Latest headlines and exclusive stories In-depth analyses and award-winning multimedia content Get access to all with our no-contract promotional package at only $0.99/month for the first 3 months* Subscribe now *Terms and conditions apply.

Man who allegedly refused to wear mask in Sentosa bar to be charged with being public nuisance

aseanpr 13 3 月

2 minutes

SINGAPORE - A 48-year-old man was scheduled to be charged in court on Saturday (March 13) with being a public nuisance and refusing to wear a mask in a bar at Sentosa. On Thursday, the police were alerted to an incident where the man allegedly refused to put on a mask despite being asked to do so by staff of a bar in Siloso Beach Walk. Preliminary police investigations showed he had also allegedly pointed his middle finger at a safe distancing ambassador (SDA) after being asked to put on his mask. The man is scheduled to be charged with causing a public nuisance, and if convicted, can be jailed for up to three months and/or fined up to $2,000. He can also be charged with intentionally causing alarm for his abusive behaviour towards the SDA. For this, he can be fined up to $5,000 and/or jailed for up to six months. The man can also be charged with refusing to wear a mask - an offence under the current Covid-19 regulations. If convicted, he can be fined up to $10,000 and/or jailed for up to six months. Police investigations into his second and third charges are ongoing. On Saturday morning, the police said they take a stern view of abuse directed at SDAs and that offenders will be de...

S’pore stretches healthcare dollar with targeted subsidies

aseanpr 13 3 月

1 minute

SINGAPORE - Healthcare spending has sometimes been compared to a balloon - squeeze it in one area and a bulge appears in another. The analogy speaks to how difficult it is to rein in rising healthcare costs, a challenge that Singapore has become increasingly familiar with as its population greys. Please subscribe or log in to continue reading the full article. Get unlimited access to all stories at $0.99/month Latest headlines and exclusive stories In-depth analyses and award-winning multimedia content Get access to all with our no-contract promotional package at only $0.99/month for the first 3 months* Subscribe now *Terms and conditions apply.

Blockpass Supports DuckStarter’s Participating IDOs With Compliance Services

indie 12 3 月

5 minutes

HONG KONG, Mar 12, 2021 - (ACN Newswire via SEAPRWire.com) - Blockpass is excited to reveal it will be working with a number of new solutions and companies as it provides compliance options to Initial DEX Offerings (IDOs) on the DuckStarter platform. As DuckDAO's token sale launchpad, the DuckStarter platform is involved with a large variety of IDOs. With Blockpass and DuckDao working together, KYC and AML provision will be quickly and easily accessible to all participants, ensuring security and regulatory compliance in the space.DuckDAO is a community-backed incubator powered by an expansive network of investors in the digital asset ecosystem. DuckStarter is a token sale launchpad where users can access both public and special rounds for high-quality crypto projects. DuckStarter will act as the final bridge between early-stage projects and the community before the project goes fully public. DuckStarter has a unique level system which requires users to lock-in a certain amount of DUCK tokens to participate in the launch platform. DuckStarter has already helped launch a number of projects and has many more lined up, including PolkaFoundry, keyTango, Lepricon, and Cash Tech.Blockpass...

Ministry of Health, Labour and Welfare Grants Orphan Drug Designation in Japan to Anti-Cancer Agent Lenvima (Lenvatinib) With Prospective Indication for Uterine Body Cancer

ruth 12 3 月

2 minutes

TOKYO, Mar 12, 2021 - (JCN Newswire via SEAPRWire.com) - Eisai Co., Ltd. announced today that it has received orphan drug designation for LENVIMA (generic name: lenvatinib mesylate), the orally available multiple receptor kinase inhibitor discovered by Eisai, with a prospective indication for uterine body cancer, by the Ministry of Health, Labour and Welfare (MHLW).In Japan, the estimated number of patients with uterine body cancer is approximately 30,000.1 It is estimated that in 2020, there were more than 17,000 new cases of uterine body cancer and more than 3,000 deaths from the disease.2 It is considered that more than 90% of uterine body cancers occur in the endometrium.3The pivotal Phase 3 Study 309/KEYNOTE-775 evaluated LENVIMA in combination with KEYTRUDA (generic name: pembrolizumab) in patients with advanced endometrial cancer (advanced uterine body cancer in Japan), following at least one prior platinum-based regimen in Japan, the United States, Europe and other countries. In this study, LENVIMA plus KEYTRUDA met its dual primary endpoints, overall survival (OS) and progression-free survival (PFS), as well as its secondary efficacy endpoint of objective response rate (OR...

Travel corridors for vaccinated passengers could open in 2nd half of 2021: Ong Ye Kung

aseanpr 12 3 月

5 minutes

SINGAPORE - Bilateral travel corridors for vaccinated passengers from places with low to moderate infection rates may well happen in the second half of this year, said Transport Minister Ong Ye Kung on Friday (March 12) as Singapore continues to explore ways to open up its borders and revive air travel. In an interview with Money FM 89.3, Mr Ong said stay-home notices and other quarantine measures will kill travel. Singapore, he added, needs to find ways to get rid of such requirements, a point he also made last week during the debate on his ministry's budget. "Nobody is going to come to Singapore and stay for 14 days," he told radio DJ Elliott Danker. While vaccinations are changing the game, this needs to work in tandem with other measures such as testing, movement restrictions and identifying countries that are "safe" and have successfully controlled the virus, Mr Ong said. For example, Singapore could open up to travellers from places with moderate Covid-19 infection rates but have ongoing vaccination programmes. "(Combine that) with testing, and you can possibly open up a safe travel corridor," he added. On air travel bubbles, Mr Ong said such arrangements require reciprocity,...

HDB calls for sixth tender to install solar panels on 1,198 HDB blocks, 57 government sites

aseanpr 12 3 月

4 minutes

SINGAPORE - In its latest push to generate more clean energy in Singapore, the Housing Board (HDB) has called for its sixth tender to install solar panels across 1,198 HDB blocks and 57 government sites on Friday (March 12). This is to meet demand for the production of a total solar capacity of 70 megawatt-peak (MWp) across government sites and HDB blocks managed by Sembawang, Tampines and Tanjong Pagar town councils. Government sites that will participate in this tender include 40 primary and secondary schools, as well as the Tuas South Desalination Plant and Kallang Fire Station. It comes under the Government's SolarNova programme, which compiles solar demand from various agencies to enjoy economies of scale, and is jointly led by HDB and the Singapore Economic Development Board (EDB). As part of this tender, vendors will be required to install smart electrical sub-meters in HDB blocks to track energy consumption patterns and the performance of common services such as lifts, lights and water pumps in each block. With this data, the HDB and respective town councils will then be able to optimise maintenance cycles of these common services, as well as detect anomalies such as equipm...

HSBC bosses try to quell banker anger over bonus cuts

elean 12 3 月

4 minutes

LONDON (BLOOMBERG) - HSBC Holdings' chief executive officer Noel Quinn and his top lieutenants were forced to defend bonus cuts to unhappy investment bankers and traders after a year marked by hectic dealmaking and volatile markets. On calls last week with staff at its global banking and markets division, Mr Quinn, along with the unit's co-heads, Georges Elhedery and Greg Guyett, had to justify why the pool had to be scaled back at the only division that saw revenue increase last year, according to people familiar with the situation. The executives told employees that the pandemic had eroded the bank's overall performance and, combined with the stark economic backdrop, meant it couldn't pay more, said the people, declining to be named detailing a private call. Even some bankers who gained top marks for their performance were told that their bonuses would be cut and that they shouldn't expect a pay increase, they said. A spokesman for HSBC declined to comment. European lenders have been made acutely aware of the consequences of attempting to pay large sums to traders and bankers against the backdrop of the worst economic conditions in decades. Deutsche Bank scaled back plans for its...

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